PREVALENCE OF HEPATITIS B VIRUS AMONG MALE AND FEMALE PATIENTS OF MEDICAL CENTRE GURKU MARARABA, NASARAWA STATE

 SOLD BY: Excellent Project| ATTRIBUTES: Title, Abstract, Chapter 1-5 and Appendices|FORMAT: Microsoft Word| PRICE: N3000| BUY NOW |DELIVERY TIME: Within 24hrs. For more details Chatt with us on WHATSAPP @ https://wa.me/2348055730284

PREVALENCE OF HEPATITIS B VIRUS AMONG MALE AND FEMALE PATIENTS OF MEDICAL CENTRE GURKU MARARABA, NASARAWA STATE

ABSTRACT

This study determine the prevalence of Hepatitis B virus among the male and female patients of the Medical Centre Gurku Mararaba Nasarawa state, Nigeria. A total number of two hunred samples were tested for the viral infection blood sample were collected using needle intravenous and one Hepatitis B test strip, serum was be used to test for the virus. The prevalence determine under the age range of 25-80 years male and female.the prevalence was higher among the patients in the age range 25-36which could be as a reflection of a high sexual activities,and also sharing of things such as clothes can increase the risk of contacting this infectious virus. To tackle this menace, unprotected sex with an infected partners and with multiple sex partners should be avoided, screening and testing of blood donor and sharing of sharp object among individuals should be discourage.And also regular medical check up should be done so as to know your status,HBV is an infectious diseases which people should be educated on how to relate with those that are carriers.

CHAPTER ONE

1.1       INTRODUCTION

Hepatitis B is an infectious disease affecting the liver, caused by the Hepatitis B virus (HBV). The infection is often  asymptomatic, but chronic infection can lead to scarring  of the liver and ultimately to cirrhosis, which is generally apparent after many years in some cases those with cirrhosis will go on to develop liver failure, liver cancer or even life threatening (Perz et al, 2004).

The virus persists in the liver, in about 85% of those that are infected. This persistent of infection can be treated with medications: the standard therapy is a combination of peg interferon and ribavirin, with either boceprevir or telaprevir added in some cases 50-80% of people treated is cured. Those who develop cirrhosis or liver cancer may require a liver transplant. Hepatitis B is the leading reason for liver transplantation (Desenclois, 2000).

Historical, patient with hepatitis, without serological evidence of hepatitis A infection, initially describe in recipient of blood or blood product are classified as non A hepatitis. This was only possible following the development of diagnostic serological test for Hepatitis A in 1965 (Perz et al, 2004), In 1989, an agent of the non A viral Hepatitis was identified as RNA virus with immunological specificity for transfusion associated with non A viral Hepatitis. Among complementary DNA fragments cloned in Escherichia Coli from the pellets of chimpanzee plasma with usually high infectivity, one clone expressed protein that reacted with the antibody (Ab) in convalescent serum, but not the pre-illness serum from chimpanzee with experimentally include the non –A viral Hepatitis. This virus seemed to be single standard RNA virus with a genome of approximately 10,000 nucleoides. The clinical importance of HBV infection is due to viral persistence in approximately 85% of those infected and the significant risk of subsequent development of chronic irreversible liver damage (Mc Quilan et al, 1997).

The risk factor presently cited as accounting for the bulk of HBV transmission worldwide are through contact with an infected person. And transmission of HBV infection through pre-natal, occupational and sexual exposure occur with much exposure regard less of the geographic areas (Kesson, 2002).

The prevalence of Co-factor known to accelerate the progression of chronic Hepatitis B virus among infected people, particularly HIV co infection, HCV co infection and alcohol consumption is likely to have impact on the overall burden to the disease. Data from the developed world suggest that HIV co infection and alcohol consumption are common among HBV infected people. The epidemiology of these co factors  among HBV infected people in the developing world has not been well defined and would be an important area of future research (kesson, 2002).

Most of the burden of HBV infection is realized through the development of chronic liver disease and Hepatocellular carcinoma (HCC) in a subset of infected people decades after initial acquisition of the infection HBV infection has already been implicated in the rising incidence and HCC and chronic liver disease in several developed countries, and many other have projected a steady rise in the incidence of HBV related complications in the coming decades (halim et al, 2000).

1.2       CLASSIFICATION OF HEPATITIS B VIRUS

Group             –           DS DNA

Family             –           Hepadna viridac

Genus              –           Orthohepadnavirus

Species            –           Hepatitis B virus

Size                 –           42nm (Mason, W. SA. et al 2008)     

1.3       AIM OF THE STUDY

The aim of the study is to analyze the hepatitis B virus (HBV) among male and female patients in medical centre Gurku Mararaba, Nasarawa state.

1.4       OBJECTIVES OF THE STUDY

1.         To determine the presence of hepatitis B virus among male and female adults

2.         To analyze the prevalence of hepatitis B virus in relation to the demographic factors of the population            

3.         To examine the dynamic of hepatitis B virus

1.5       JUSTIFICATION OF THE STUDY

An epidemic of hepatitis B virus can cause mortality and this could lead to reduction in the population of the country. And also the economy could be affected. Because the health of the citizens is judge by the health of the economy. It also has a lot off impact on the patients immune system due to inability  of the body to carryout it’s normal body functions, the family of the patient will be affected as well because, all their earnings will be diverted to the treatments of the patient.

 SOLD BY: Excellent Project| ATTRIBUTES: Title, Abstract, Chapter 1-5 and Appendices|FORMAT: Microsoft Word| PRICE: N3000| BUY NOW |DELIVERY TIME: Within 24hrs. For more details Chatt with us on WHATSAPP @ https://wa.me/2348055730284